Ka la 9 Pulungoana 2021, mofuta o mong oacoronavirus e ntjhaB.1.1.529 e fumanwe kgetlo la pele ho tswa ho sampole ya nyewe ya Afrika Borwa.Ka nako e ka tlase ho libeke tse 2, mofuta ona oa phetoho o fetohile mofuta o ka sehloohong oa tšoaetso e ncha ea Afrika Boroa, 'me kholo ea eona e potlakileng e tsositse tlhokomelo ea lefats'e.Ka la 26 Pulungoana, mofuta ona o fetotsoeng o hlalositsoe ke WHO e le "mofuta oa bohlano oa ho ameha" (VOC), o bitsoang Omicron (Omicron) mutant.Hajoale, mofuta o fapaneng oa Omicrom o nametse ka potlako linaheng kapa libakeng tse 19 lefatšeng ka bophara, 'me e ka hlahisa mathata a macha a thibelo le taolo ea seoa sa lefats'e.
WHO e boetse e boletse hore Omicron e na le palo e kholo ea liphetoho, tse ling tsa tsona li tšoenyang.WHO e boetse e boletse hore mofuta o fetotsoeng oa "Omicron" o bonoa ka potlako ho feta mefuta e meng e fetotsoeng e bakileng ts'oaetso ea ts'oaetso nakong e fetileng, e bonts'a hore mofuta ona oa morao-rao oa phetoho o ka ba le monyetla oa kholo.Ho thibela ka tieo ho ata ha mofuta o feto-fetohang oa coronavirus e ncha Omicron e fetohile sepheo se secha sa thibelo ea seoa sa lefats'e.
'Mapa oa kabo ea phetoho ea Omicron(1)le Delta(2), Univesithi ea Stanford Coronavirus le Database Resistance Resistance Database
Ntle le ho ba le liphetoho tse ngata ho protheine ea spike, mofuta oa Omicron mutant o boetse o na le libaka tse ngata tsa phetoho ho protheine ea N.Kaha sepheo sa mantlha sa "coronavirus antigen reagent" e ncha ke protheine ea N, phetoho ea protheine ea N e ka ama antigen e ncha ea coronavirus.Ho nepahala ha lisebelisoa tsa tlhahlobo ho na le tšusumetso.
Letlapa la 1. Papiso ea phetoho ea protheine ea N ea liphetoho tse fapaneng
| |
Mofuta wa vaerase
| N phetoho ea protheine |
Alfa(B.1.1.7) | R203K;G204R;(>50%) S194L(5-50%) D3H;D63G;T205I;M234I(1-5%) |
Beta(B.1.351) | T205I (>50%) P13S;T3621(5-50%) Q9H;Q28R;A35T;E38V;Q418H (1-5%) |
Gamma(leq.1) | P80R;S202C;R203K;G204R (>50%) A211S;D402Y;S4131 (1-5%) |
Delta(B.1.617.2) | D63G;R203M;G215C;D377Y (>50%) Q9L(>5-50%) G18V;R385K (1-5%)
|
Omicron(B.1.1.529) | P13L;R203K;G204R E31/R32/S33 Del |
Ha ho bapisoa le protheine ea Alpha-N, protheine ea Omicron-N e na le phapang ea maemo a 10 a amino acid.Bakeng sa ho batlisisa ts'ebetso ea ts'ebetso ea protheine ea Omicron-N ka thepa e tala ea anti-covid-19 ea mofuta oa Keygen, re lokisitse protheine e ncha ea Omicron-N lekhetlo la pele, 'me ra etsa netefatso e kopanetsoeng ke Keygen Gene le bareki ba bangata.Liphetho li bonts'a hore ponahalo e bulehileng ea mofuta o mocha oa antibody e na le liphetho tse tšoanang tsa ho lemoha protheine ea Omicron-N, protheine ea Alpha-N le protheine ea Delta-N.The open view gene new crown antibody material e ka etsa bonnete ba ho nepahala ha thipa e ncha ea antigen bakeng sa ho lemoha mefuta e sa tšoaneng ea Omicron..
Letlapa la 2 Liphetho tsa ho fumanoa ha Omicron recombinant N protein ka neocorona antibody | ||||||
Sethibela mmele E kopanetsoe | Alpha-Nprotein | Omicron-Nprotein | ||||
4.0ng/ml | 2.0ng/ml | 1.0ng/ml | 4.0ng/ml | 2.0ng/ml | 1.0ng/ml | |
Morero 1 | G5 | G4 | G2 | G5 | G4 | G2 |
Morero 2 | G5 | G4 | G2 | G5 | G4 | G2 |
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Nako ea poso: Dec-14-2021